Dhcr24^{tm1c(EUCOMM)Wtsi}

The L1L2_st0 cassette was inserted at position 106428382 of Chromosome 4 upstream of the critical exon 3 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 3 at position 106429001. The critical exon 3 is thus flanked by loxP sites. A "conditional ready" (floxed) allele is created by flp recombinase expression in mice carrying this allele. (J:304449)