CRISPR/Cas9 endonuclease-mediated genome editing is used to insert an IRES-Cre recombinase sequence followed by a polyA signal after the stop codon (at the end of exon 11). (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count