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The transgenic construct contains a modified full length mouse Usp14 cDNA (including the Usp14 Kozak sequence) under the control of the pan-neuronal Thy1 (Thy1.2) promoter. The Usp14 sequence is modified to change the active site cysteine to an alanine (C114A) at position 114. (J:306115)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
