The targeting construct is designed to contain from 5' to 3'; an FRT site, a loxP site, a PGK-neomycin resistance cassette, an FRT site, a loxP site, inserted into intron 2. A third loxP site is inserted in intron 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 3 floxed. (J:305949)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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