The bacterial artificial chromosome, RP23-406B15, containing Nanog and its regulatory sequences was modified to insert a cDNA encoding Cre/Esr1* fusion protein into the translation initiation start site. Additional sequencing indicates that the fusion is not ERT2, but appears to be a mutant derivative of the mouse estrogen receptor. (J:248397)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count