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EN
The targeting vector is designed to insert an amino acid substitution at position 165 altering alanine to valine (A165V; chr14:34571772 C to T; GRCm38/mm10) into exon 6. The substitution is followed by a loxP-flanked neomycin cassette in intron 6. Cre-mediated recombination removed the loxP-flanked neo cassette. (J:305082)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
