Tg(Neurod4-cre/ERT2)D4ATahi

The transgene was constructed using a genomic BAC clone RP23-55O18 encoding the mouse neurod4 gene by inserting a CreERT2 cassette at the first ATG sequence of exon2 and the loxP site in the vector backbone (pBACe3.6) was deleted by replacement with the zeocin resistance gene. The five mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G1C) was selected by the highest recombination rate. (J:306016)