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The transgene was constructed using a genomic BAC clone RP24-347K19 encoding the mouse neurogenin (Neurog)1 gene by replacing the entire coding sequence in exon1 with a CreERT2 cassette and the loxP site in the vector backbone (pTARBAC) was deleted by replacement with the zeocin resistance gene. The eleven mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G1C) was selected by the highest recombination rate. (J:306016)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
