The tetracycline response element (TRE) was connected to a GFP gene containing a palmitoylation sequence of GAP43 N terminally, and the construct was flanked by 2xcHS4 insulators. A targeting vector, the 2xcHS4 TRE-mGFP with an frt-flanked neomycin resistant gene was introduced into the HK3i embryonic stem cells derived from C57BL/6. (J:288786)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NJcl
Targeted
Insertion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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