A GFP reporter gene was inserted in-frame with the 5' end of the gene's coding sequence. The upstream conserved non-coding sequence 0 (CNS0 (Rr122); a STAT5-binding enhancer located at chrX:7,570,6747,571,274 (GRCm38) within intron 1 of Ppp1r3f) was flanked upstream by a loxP site and downstream by an FRT site flanked neomycin resistance gene cassette and a second loxP site. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed CNS0. (J:305560)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion, Intragenic deletion
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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