The targeting vector contains a Cre recombinase/ERT2 fusion, a viral 2A oligopeptide that mediates ribosomal skipping, and a tdTomato reporter followed by neomycin resistance cassette inserted after the ATG site in exon 1. The insertion deletes 200 bp of the coding sequence rendering the allele null. (J:94077, J:313017)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion, Intragenic deletion
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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