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An FRT-flanked neomycin selection cassette replaced the 3' part of the transcript and loxP sites flanking the whole gene were inserted to allow a full deletion on top of the partial deletion. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the floxed region which results in a fully deleted region (the RNA, the CpG island, and part of the upstream region). (J:304782)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
