LoxP sites were inserted in front of exon 2 and immediately after the termination codon. In addition, an FRT-flanked neomycin resistance selection cassette was inserted and removed via Flp-mediated recombination. (J:303692)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count