Exon 2 was flanked by loxP sites and an frt-flanked neomycin selection cassette was inserted 3' to exon 2. The neomycin selection cassette was removed via FLP1-mediated recombination in the germline. (J:299944)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count