Exon 3-5 were flanked by loxP sites and a neomycin resistance cassette flanked by FRT sites and a puromycin resistance cassette flanked by F3 sites were introduced in intron 2 and intron 5, respectively. Flp-mediated recombination removed the selection markers. (J:282882)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count