The single coding exon was deleted via Cre-mediated recombination of flanking loxP sites. RNA in situ hybridization confirmed the absence of transcript expression in E12.5 homozygous mutant embryos. (J:303998)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count