A loxP site was inserted upstream of exon 8 and an FRT-flanked neomycin resistance gene cassette and a second loxP site were inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette leaving exon 8 floxed. (J:289548)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count