BAC recombineering is used to create a targeting construct that contains a loxP site followed by a betageo cassette (a fusion of beta-galactosidase and neomycin phospotransferase II) inserted into intron 5. A second loxP site is inserted in intron 6. (J:304050)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count