The 3' UTR of Ddx19a and intron 5 of Ddx19b were targeted with two sgRNAs (targeting CTGACAACTGCCAAGAATGGTGG and GGCTCAGAGGTTAAAAGCATGGG) using CRISPR/Cas9 technology, resulting in the deletion of 39,002 bp of sequence including the entire coding region of Ddx19a and the 3' end of Ddx19b. (J:289833)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Endonuclease-mediated
Intergenic deletion, Intragenic deletion
--
2
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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