LoxP sites and an frt-flanked neomycin selection cassette was inserted to flank exons 4-5. The frt-flanked neomycin selection cassette was deleted via FLP1-mediated recombination in the germline. (J:301755)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count