Codons 483-488 were deleted and a downstream Neo cassette (NeoR) flanked by LoxP sites was inserted. The neomycin selection cassette was removed via Cre-mediated recombination in the germline. (J:234112)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count