The first 150 amino acids encoded within exon 2 were replaced with an IRES-lacZ-neo cassette. Immunohistochemical analysis confirmed the absence of encoded protein in the perinuclear regions of spermatocytes and round spermatids from homozygous mutant male mice. (J:301856)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count