CRISPR-targeting with a donor plasmid inserted upstream of exon 11 an FRT site, splice acceptor, IRES, lacZ reporter gene, polyadenylation sequence, loxP site, hbactp promoter driving a neomycin resistance cassette, polyadenylation sequence, FRT site, and loxP site. An additional loxP site was inserted downstream of exon 11. (J:285251)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count