Plasmids encoding a guide RNA (CGAGGCATAAAGGCCCTGTA) are designed to insert a viral 2A oligopeptide (P2A) self cleaving peptide, that mediates ribosomal skipping, followed by a human diphtheria toxin receptor (DTR) immediately upstream of the endogenous stop codon. (J:309477)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count