Exon 8 was flanked by loxP sites and a neomycin cassette flanked by FRT sites was inserted downstream of exon 1 but before the second loxP site. Flp-mediated recombination removed the neomycin cassette leaving exon 8 floxed. (J:303316)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count