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The targeting vector is designed to insert a loxP-flanked neomycin cassette and an EGFP reporter onto a portion of exon 7 (prior to the transmembrane domains) and to replace all of exon 8. Northern analysis of liver, lung, spleen, heart, eye, brain, testes, and kidney detected multiple short transcripts. Cre-mediated recombination removed the floxed neo cassette. The EGFP reporter does not appear to express. (J:255568)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
