CRISPR/Cas9 genome editing technology was used to generate a large 902 bp deletion. Western blot analysis confirmed the absence of protein expression in the testes and cauda epididymal spermatozoa from homozygous mutant male mice. (J:303071)
Basic Information
(129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count