LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exons 3-4. The flanked region was deleted via Cre-mediated recombination in the germline. Approximately 20% of truncated Nexn was present with respect to Nexn levels in controls. (J:301807)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count