Exon 2 was targeted with two sgRNAs (targeting ATCTTGGCCCGATGTTTAGC and GGCTAAACATCGGGCCAAGA) using CRISPR/Cas9 technology, resulting in a 10 bp deletion (GATGGACGAT) that leads to a frameshift and premature stop codon. (J:299228)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count