Exons 3 and 4 were flanked by loxP sites and an frt-flanked neomycin cassette was inserted upstream of exon 3. Flp-mediated recombination removed the neomycin cassette and left exons 3-4 floxed. (J:292575)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count