CRISPR/cas9 genome editing is used to insert a T2A peptide sequence and Cre recombinase at the stop codon. T2A sequence adds EGRGSLLTCGDVEENPG to the C terminus of Adora1 and a proline to the N terminus of cre. (J:300669)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count