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CRISPR/Cas9 mediated genome editing technology was used to delete exon 3. Immunofluorescence microscopy analysis confirmed the absence of protein in respiratory cilia of the trachea, multiciliated epithelia of the Fallopian tube, and multiciliated ependyma of the brain in homozygous mutant mice. (J:297786)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
