Nlrc4^em3Vnce

别称:

Nlrc4^S533D

Nlrc4^{em3(S533D)Vnce}

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Basic Information

Phenotypes

References Literature

Serine codon 533 (TCA) was targeted with an sgRNA (targeting CTCTGGAGGCAGGAATCAAT) and ssODN templates using CRISPR/Cas9 technology, changing it to aspartic acid codon GAT (p.S533D). This mutation creates a phosphomimetic residue at this position. Western blot experiments confirmed the expression of peptides from this allele. (J:294930)

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