A single loxP site was inserted 3' to exon 15 and a floxed neomycin selectable marker cassette was inserted 204 bp downstream of exon 11 and 200 bp upstream of exon 12. Exons 11 - 15 encode the Ser/Thr kinase domain. (J:236420)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count