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EN
A Lox-flanked transcriptional blocking cassette consisting of a splice acceptor (SA), an internal ribosomal entry site (IRES), and an EGFP gene with a poly(A) signal (pA) was inserted into the intron between exons 2 and 3. In the absence of Cre recombinase, expression of the targeted allele is suppressed generating a null allele. A neomycin resistance cassette was removed by Flp-mediated recombination in the germline. (J:251956)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
