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CRISPR/Cas9 technology generated a deletion of exon 45 of the human DMD in Tg(DMD)72Thoen mice. Two founders were used to establish lines, however the pound symbol (#) is used when line is not specified and/or lines are pooled. The transgene integrated on chromosome 5 in a tail to tail duplication. (J:280218)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
