LoxP sites were inserted in introns 1 and 2 using synthetic crRNA, tracrRNA and ssODNs with CRISPR/Cas9 technology. (J:302012)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count