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EN
CRISPR/Cas9 technology generated an isoleucine (ATC) codon to a threonine (ACA) codon at position 685 (I685T) in exon 21. An additional base change in the third position of the following glycine codon was introduced to eliminate the Cas9 PAM sequence to prevent retargeting. (J:300000)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
