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Two transgenic constructs carrying mouse Lta and Ltb cDNA, respectively, under the control of the rat Cela1 (formerly Ela1) promoter are co-injected into C57BL/N zygotes. Founder lines 40 and 58 were established. Founder 58 is the high-expressing line. Southern blot analysis indicates that 3 copies of the transgene were integrated in the mouse genome. (J:301576)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
