A loxP site was inserted 5' to exon 8 and a second loxP site and an frt-flanked neomycin selection cassettte were inserted 3' to exon 9. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:260660)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count