The transgenic vector contains a modified human ACTA1promoter driving expression of full-length mouse Thbs4 cDNA. The modified promoter incorporates 2 kb of 5' flanking sequence, 90 bases of 5'-UTR, and 149 bases of IVS1 (intervening sequence 1) from the human ACTA1 gene. (J:238094)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count