The transgene consists of human BAC RP11-120C17, containing the 3' end of the FAM3B gene, the complete MX2 and MX1 genes, and the 3' end of the TMPRSS2 gene. The MX2 gene is a null allele in these transgenic mice owing to an unintentional deletion that includes exon 4. (J:242012)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x SJL
--
Insertion
--
2
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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