The transgene consists of human BAC RP11-120C17, containing the 3' end of the FAM3B gene, the complete MX2 and MX1 genes, and the 3' end of the TMPRSS2 gene. The MX2 gene is a null allele in these transgenic mice owing to an unintentional deletion that includes exon 4. (J:242012)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count