The targeting vector inserted a T2A sequence, improved cre recombinase gene inserted between the last amino acid of of the coding sequence and the termination sequence. Flp-mediated recombination removed an FRT-flanked puromycin resistance cassette inserted downstream of the stop codon. (J:273209)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count