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The transgene construct comprises genomic sequence for the mouse Thy1 promoter (270 bp upstream of transcription start), 5' UTR exons and introns and 3' UTR sequences flanking the fluorescent protein gene. The mEGFP gene consists of sequence coding for the first 40 amino acids of the Marcks gene (modified to include palmitoylation sites at residues 3 and 4), which provides plasmalemmal targeting, fused to EGFP gene sequence. This transgene is almost exclusively expressed in the nervous system. (J:135512)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
