The transgene comprises a 400-kb yeast artificial chromosome (YAC) RCA1 that contains the human 50-kb CD46 gene and the preceding CR1-like and MCP-like genetic elements. (J:160878)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count