Exons 4-10 were floxed, with a neomycin resistance gene and one loxP site inserted in the intron upstream of exon 4 and the other lox P site in the intron downstream of exon 10. Cre and Flp-mediated recombination removed the neomycin cassette and exons 4-10. (J:299380)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count