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A deletion in the 3' end of the coding region was created using sgRNAs (targeting TACAGGCGGGAGCAGAA and ACGACCAGAACGAAGAGG) with CRISPR/Cas9 technology. The deletion removes 44 codons (132 bp), from K97 through E140, from the 3' end of the coding region, representing most of the negatively charged tail of the encoded peptide. (J:298827)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
