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The 8.4kb construct incorporates the mouse Col2a1 promoter and a fragment of intron 1 ligated to a splice acceptor sequence followed by an internal ribosomeentry site (IRES), tetracyclinecontrolled transactivator (tTA), and the SV40 large T antigen polyadenylation signal. A single copy of the transgene was inserted 16 kb downstream of Peli2 on mouse Chromosome 14. Line H is the high expresser line. (J:320594)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
