This targeted transgene overexpresses Cas9 ubiquitously by integrating a CAG-Cas9 construct at the Gt(ROSA26)Sor locus via PhiC31 integrase cassette exchange in embryonic stem cells. (J:245962)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count