The knock-in allele contains a human Diptheria Toxin receptor (HBEGF) driven by the endogenous promoter and followed by an IRES sequence then the endogenous coding sequence. Cre-recombination removed the floxed neomycin selection cassette. (J:266723)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count